Overview of Semaglutide
One of the most powerful medications used in modern medical weight loss is semaglutide, an innovative glucagon-like peptide-1 (GLP-1) analogue that enhances satiety signals in the brain. It is self-administered as a simple weekly injection.
Originally developed for diabetes treatment under the brand names Ozempic and Rybelsus, semaglutide has shown remarkable efficacy for weight loss and appetite control in numerous clinical trials.
In 2021, the FDA approved Wegovy, a higher dosed semaglutide specifically for chronic weight management. However, due to incredible demand and limited manufacturing capacity, obtaining brand name semaglutide can be very challenging.
Fortunately, Rejuvenate Clinic has access to pharmacy-grade semaglutide, allowing us to provide this breakthrough medication to those eager to benefit from its profound effects on regulating eating behaviors and calorie intake.
Semaglutide is a GLP-1 medication used for diabetes and obesity that acts on appetite regulation pathways in the brain to powerfully suppress hunger and food cravings.
Mechanism of Action
As a GLP-1 receptor agonist, semaglutide activates key neurons in the hypothalamus, hindbrain, and gastrointestinal tract impacting energy intake and storage.
It works via three complementary physiological mechanisms:
- Slowing gastric emptying so that nutrients take longer to digest, increasing satiety after meals
- Activating satiety signals and reducing feelings of hunger in the brain
- Improving insulin sensitivity, allowing for more efficient carbohydrate metabolism and fat burning
This multi-pronged approach translates into effortless calorie deficit, better blood sugar balance, and accelerated fat loss compared to lifestyle interventions alone. It empowers patients to establish healthy eating habits free from overwhelming hunger and cravings.
Physiological Effects |
Clinical Outcomes |
Slows gastric emptying |
Earlier satiation after smaller meals |
Activates satiety centers |
Marked suppression of appetite and hunger |
Improves insulin sensitivity |
Stabilized blood glucose levels, increased fat metabolism |
Semaglutide tackles weight loss on three fronts - slowing digestion, suppressing appetite, and optimizing carbohydrate metabolism for faster results.